The association between glycemic index and glycemic load and quality of life among overweight and obese women: a cross-sectional study

BMC Nutrition

Research

Cain C. T. Clark¹  Melika Fallah²  Niloufar Rasaei²  Fatemeh Gholami²  Mehdi Karimi²  Khadijeh Mirzaei³  Niki Bahrampour⁴  Sahar Noori⁴ 

[1] Centre for Intelligent Healthcare, Coventry University, CV1 5FB, Coventry, UK;Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences(TUMS), P.O. Box, 14155-6117, Tehran, Iran;Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences(TUMS), P.O. Box, 14155-6117, Tehran, Iran;Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran;Department of Nutrition, Science and Research Branch, and Islamic Azad University, Tehran, Iran;

关键词: Quality of life;    Glycemic index;    Glycemic load;    Diet;    Overweight;    Obesity;   

DOI  :  10.1186/s40795-022-00668-8

 received in 2022-04-23, accepted in 2022-12-30,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundThe association between different dietary approaches and quality of life (QoL) has been well-demonstrated in previous research. However, the relationship between glycemic index (GI) and glycemic load (GL) with different dimensions of QoL has not been established. Therefore, we aimed to investigate the relationship between GI and GL with QoL in overweight and obese women.MethodsTwo hundred seventy-six overweight and obese women (body mass index (BMI) ≥ 30 kg/m2), aged 18–64 years old, were included in this cross-sectional study. The amount of dietary intake and GI and GL indexes were established using a valid and reliable Food Frequency Questionnaire (FFQ) containing 147 items. Body composition (using bioimpedance analysis), anthropometrics, and physical activity were assessed. Insulin resistance (HOMA-IR) and hs-CRP were also measured, whilst QoL was measured using the SF-36 (short-form-36), self-administered, questionnaire.ResultAnalyses were performed using multivariable linear regression, considering a wide range of confounding variables, such as age, physical activity, BMI, education, job, smoking, and marriage. We found a significant negative association between glycemic load and quality of life (β = -0.07, 95%CI = -0.13_ -0.01, p = 0.01). No significant associations were observed between glycemic index and quality of life (β = -0.03, 95%CI = -0.81_ 0.75, p = 0.93).ConclusionWe observed a significant negative association between QoL and GL, but not GI, among overweight and obese women in Iran. Our results need to be confirmed with further well-designed and adequately powered studies that control for clinical confounders.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 1