Antibiotic resistance profile of common uropathogens during COVID-19 pandemic: hospital based epidemiologic study

BMC Microbiology

Research

Sherief El-Ghannam¹  Mahmoud Hussein²  Walaa Mohamed Omar Ashry³  Ahmed Yousef⁴  Ahmed M. Abdel Gawad⁵ 

[1] Department of Clinical Pathology, Damietta Faculty of Medicine, Al-Azhar University, New Damietta City, Egypt;Department of Forensic Medicine and Clinical Toxicology, Damietta Faculty of Medicine, Al-Azhar University, New Damietta City, Egypt;Department of Medical Microbiology and Immunology, Damietta Faculty of Medicine (Girls), Al-Azhar University, New Damietta City, Egypt;Department of Public Health and Community Medicine, Damietta Faculty of Medicine, Al-Azhar University, New Damietta City, Egypt;Department of Urology, Damietta Faculty of Medicine, Al-Azhar University, New Damietta City, Egypt;

关键词: Antimicrobial resistance;    Antimicrobial stewardship;    COVID-19;    Uropathogens;    Urinary tract infection;   

DOI  :  10.1186/s12866-023-02773-5

 received in 2022-09-22, accepted in 2023-01-13,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundAntimicrobial resistance has a direct impact on the ability to treat common infections, and this was worsened during the COVID-19 pandemic. Worldwide surveillance studies are lacking and resistance rates vary spatially, so frequent local surveillance reports are required to guide antimicrobial stewardship efforts.This study aims to report our common local uropathogens and their antibiogram profiles in our community during the COVID era.MethodsA retrospective study included patients referred to our urology units with urine culture and sensitivity. All bacterial strains were identified, and their antibiotic susceptibilities were tested.ResultsOut of 2581 urine culture results recruited, 30% showed microbiological proof of infection. The majority, 486 (63.4%), were isolated from females. The most frequent isolates were Escherichia coli (44.4%) and Staphylococcus aureus (17.8%). The resistance rates ranged from 26.9 to 79.7%. Piperacillin-tazobactam antibiotic had the lowest resistance rate. The multi-drug resistance pattern was recorded in 181 (23.9%) of the isolates; 159/597 (26.6%) Gram-negative and 22/160 (13.8%) Gram-positive isolates.ConclusionsAlarming rates of antimicrobial resistance were detected, which stresses the significance of following infection control policies and establishing national antimicrobial stewardship standards.

【 授权许可】

CC BY   
© The Author(s) 2023