Global burden of prostate cancer attributable to smoking among males in 204 countries and territories, 1990–2019

BMC Cancer

Research

Jiangtao Wu¹  Dingping Huang²  Yingfeng Zhang³  Hanfei Zhang⁴  Daqing Hong⁵  Xia Wang⁶ 

[1] Department of Urology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China;Department of Urology, Zhongshan Hospital, Xiamen University, Xiamen, China;School of Medicine, University of Electronic Science and Technology of China, Chengdu, China;School of Medicine, University of Electronic Science and Technology of China, Chengdu, China;Department of Nephrology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, China;School of Medicine, University of Electronic Science and Technology of China, Chengdu, China;Department of Nephrology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, China;Renal Department and Nephrology Institute, School of Medicine, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, 610072, Chengdu, China;The George Institute for Global Health, University of New South Wales, Level 5, 1 King Street, 2042, Newtown, NSW, Australia;

关键词: Burden of disease;    GBD study;    Prostate cancer;    Smoking;    Mortality;    Disability-adjusted life-years;   

DOI  :  10.1186/s12885-023-10552-8

 received in 2022-09-08, accepted in 2023-01-16,  发布年份 2023

来源: Springer

【 摘 要 】

IntroductionUnderstanding the latest global spatio-temporal pattern of prostate cancer burden attributable to smoking can help guide effective global health policy. This study aims to elucidate the trends in smoking-related prostate cancer from 1990 to 2019 using Global Burden of Disease (GBD) 2019 study data.MethodsData on prostate cancer attributable to smoking were extracted from Global Burden of Disease Study (GBD) 2019. The numbers and age-standardized rates on smoking-related prostate cancer mortality (ASMR) and disability-adjusted life years (ASDR) were analyzed by year, age, region, country, and socio-demographic index (SDI) level. Estimated annual percentage change (EAPC) was calculated to evaluate the temporal trends of ASMR and ASDR from 1990 to 2019.ResultsOf all prostate cancer deaths and DALYs globally in 2019, 6% and 6.6% were attributable to smoking, which contributed to 29,298 (95% CI 12,789 to 46,609) deaths and 571,590 (95% CI 253,490 to 917,820) disability-adjusted life-years (DALYs) in 2019. The number of smoking-related deaths and DALYs showed an upward trend, increasing by half from 1990 to 2019, while ASMR and ASDR declined in five sociodemographic indexes (SDI) regions, with the fastest decline in high SDI regions. For geographical regions, Western Europe and East Asia were the high-risk areas of prostate cancer deaths and DALYs attributable to smoking, among which China and the United States were the countries with the heaviest burden. The ASMR has decreased in all age groups, with the fastest decrease occurring in 75–79 years old. The ASMR or ASDR tended to increase in countries with the lowest SDI, but declined in countries with the highest SDI. The EAPC in ASMR or ASDR was highly negatively correlated with Human Development Index (HDI) in 2019, with coefficients 0.46.ConclusionThe number of smoking-related prostate cancer deaths and DALYs continued to increase globally, whereas its ASMR and ASDR have been decreasing. This substantial progress is particularly significant in developed regions and vary across geographic regions. Medical strategies to prevent and reduce the burden should be adjusted and implemented based on country-specific disease prevalence.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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