A comparison of international modelling methods to evaluate health economics of colorectal cancer screening: a systematic review protocol

Systematic Reviews

Protocol

Felicity Lamrock¹  Olivia Adair¹  Mark Lawler²  Ethna McFerran²  Christine McKee³  Tracy Owen³ 

[1] Mathematical Sciences Research Centre, Queen’s University Belfast, Belfast, Northern Ireland;Patrick G Johnston Centre for Cancer Research, Queen’s University Belfast, Belfast, Northern Ireland;Public Health Agency, 12-22 Linenhall Street, BT2 8BS, Belfast, UK;

关键词: Colorectal cancer;    Screening;    Cost-effectiveness analysis;    Cost-utility;    Cost–benefit;    Quality-adjusted life years;    Life years gained;    Incremental cost-effectiveness ratio;    Economic evaluation;    Health economics;   

DOI  :  10.1186/s13643-023-02173-w

 received in 2022-02-08, accepted in 2023-01-14,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundColorectal cancer (CRC) is becoming an increasing health problem worldwide. However, with the help of screening, early diagnosis can reduce incidence and mortality rates. To elevate the economic burden that CRC can cause, cost-effectiveness analysis (CEA) can assist healthcare systems to make screening programmes more cost-effective and prolong survival for early-stage CRC patients. This review aims to identify different CEA modelling methods used internationally to evaluate health economics of CRC screening.MethodsThis review will systematically search electronic databases which include MEDLINE, EMBASE, Web of Science and Scopus. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidance recommendations will design the review, and the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement will be used to extract relevant data from studies retrieved. Two reviewers will screen through the evidence using the PICOS (Participant, Intervention, Comparators, Outcomes, Study Design) framework, with a third reviewer to settle any disagreements. Once data extraction and quality assessment are complete, the results will be presented qualitatively and tabulated using the CHEERS checklist.DiscussionThe results obtained from the systematic review will highlight how different CRC screening programmes around the world utilise and incorporate health economic modelling methods to be more cost-effective. This information can help modellers develop CEA models which can be adapted to suit the specific screening programmes that they are evaluating.Systematic review registrationPROSPERO CRD42022296113

【 授权许可】

CC BY   
© The Author(s) 2023

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