Seroprevalence of anti-SARS-CoV-2 antibodies and factors associated with infection among adolescent men who have sex with men and transgender women in Salvador, Brazil

BMC Public Health

Research

Fernanda W. de M. Lima¹  Carina C. Santos¹  Helen R. S. S. Matos¹  Laio Magno²  Dulce Ferraz³  Alexandre Grangeiro⁴  Inês Dourado⁵  Fabiane Soares⁵  Marie Préau⁶  Xavier Mabire⁷  Eliana Miura Zucchi⁸ 

[1] Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal da Bahia, Salvador, Brazil;Departamento de Ciências da Vida, Universidade do Estado da Bahia, Salvador, Brazil;Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil;Escola FIOCRUZ de Governo, Fundação Oswaldo Cruz, Brasília, Brazil;Pole of Social Psychology, UMR 1296 Radiations: Défense, Santé, Environnement, Université Lyon 2, Lyon, France;PHASE (Psychology of Health, Aging and Sport Examination), Faculty of Social and Political Science, University of Lausanne, Lausanne, Switzerland;Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil;Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil;Pole of Social Psychology, UMR 1296 Radiations: Défense, Santé, Environnement, Université Lyon 2, Lyon, France;Institut de Psychologie, Université de Lausanne, Lausanne, Switzerland;Pole of Social Psychology, UMR 1296 Radiations: Défense, Santé, Environnement, Université Lyon 2, Lyon, France;PHASE (Psychology of Health, Aging and Sport Examination), Faculty of Social and Political Science, University of Lausanne, Lausanne, Switzerland;Programa de Pós-Graduação em Saúde Coletiva, Universidade Católica de Santos, Santos, Brazil;

关键词: COVID-19;    Antibodies;    Prevalence;    Men who have sex with men;    Transgender women;    Adolescent;    Brazil;   

DOI  :  10.1186/s12889-022-14969-x

 received in 2022-08-16, accepted in 2022-12-29,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundBrazil was strongly affected by the COVID-19 pandemic and the impact of the pandemic on sexual and gender minorities’ youth remains unknown. This study aimed to estimate the seroprevalence of SARS-CoV-2 antibodies and associated factors among adolescent men who have sex with men (AMSM) and transgender women (ATGW) participants of a human immunodeficiency virus (HIV) pre-exposure prophylaxis cohort study (PrEP1519).MethodsThis is a cross-sectional design conducted between June and October 2020 in Salvador, Brazil. Serum samples were collected from AMSM and ATGW aged 16-21 years between June-October 2020. IgG and IgM anti-SARS-CoV-2 were detected by chemiluminescence immunoassay, and data were collected through a socio-behavioral questionnaire.ResultsAmong the 137 participants, the seroprevalence of anti-SARS-CoV-2 IgG and IgM was 20.4%; 16.8% of the participants were positive for IgG, and 11.7% for IgM. In the multivariable analysis, the seroprevalence was two times higher among those who never wore masks (OR= 2.22; 95% CI: 1.08-4.57) and among those who believed that they could be easily cured of the disease (OR= 2.05; 95% CI: 1.05-4.01).ConclusionsThe high seroprevalence of SARS-CoV-2 antibodies among gender and sexual minority youth seems to be informed by behaviors and attitudes that contrast with public health measures and the potential severity of the disease when vaccination was still not available.

【 授权许可】

CC BY   
© The Author(s) 2023