Knowledge mobilization activities to support decision-making by youth, parents, and adults using a systematic and living map of evidence and recommendations on COVID-19: protocol for three randomized controlled trials and qualitative user-experience studies

Trials

Study Protocol

Matthew Munan¹  Lisa Hartling²  Sarah Elliott²  Jacqueline Relihan³  Matthew Prebeg³  Adrienne Stevens⁴  Ami Baba⁵  Lisa Stallwood⁵  Nancy J. Butcher⁶  Martin Offringa⁷  Tamara Kredo⁸  Miloslav Klugar⁹  Jozef Suvada^1,10  Shannon D. Scott^1,11  Dawn P. Richards^1,12  Rana Charide^1,13  Tamara Lotfi^1,13  Ashley Motillal^1,13  Lawrence Mbuagbaw^1,14  Holger J. Schünemann^1,15  Elie A. Akl^1,16  Maicon Falavigna^1,17  Joseph L. Mathew^1,18  Shahab Sayfi^1,19  Kevin Pottie^2,20 

[1] Alberta Research Centre for Health Evidence, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada;Alberta Research Centre for Health Evidence, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada;Cochrane Child Health, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada;Centre for Addiction and Mental Health, Toronto, Ontario, Canada;Centre for Immunization Readiness, Public Health Agency of Canada, Ottawa, Canada;Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada;Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada;Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada;Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada;Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada;Division of Neonatology, The Hospital for Sick Children, Toronto, Ontario, Canada;Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa;Division of Clinical Pharmacology, Department of Medicine and Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa;Czech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Centre of Excellence, Masaryk University GRADE Centre), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, 625 00, Brno, Czech Republic;Departments of Science and International Studies, St. Elizabeth University of Public Health and Social Science, Bratislava, Slovak Republic;Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada;Five02 Labs Inc, Toronto, Ontario, Canada;Canadian Arthritis Patient Alliance, Toronto, Ontario, Canada;Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main St. W, L8S 4K1, Hamilton, Ontario, Canada;Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main St. W, L8S 4K1, Hamilton, Ontario, Canada;Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada;Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada;Biostatistics Unit, Father Sean O’Sullivan Research Centre, St Joseph’s Healthcare, Hamilton, Ontario, Canada;Centre for Development of Best Practices in Health (CDBPH), Yaoundé Central Hospital, Yaoundé, Cameroon;Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town, South Africa;Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main St. W, L8S 4K1, Hamilton, Ontario, Canada;Department of Biomedical Sciences, Humanitas University, Milan, Italy;Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main St. W, L8S 4K1, Hamilton, Ontario, Canada;Department of Internal Medicine, American University of Beirut, Beirut, Lebanon;National Institute for Health Technology Assessment, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;Postgraduate Institute of Medical Education and Research, Chandigarh, India;Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada;Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada;Department of Family Medicine, Western University, London, Ontario, Canada;

关键词: eCOVID RecMap;    COVID-19;    Plain language recommendation;    Standard language versions;    Randomized controlled trial;    Knowledge mobilization;    Public engagement;   

DOI  :  10.1186/s13063-023-07067-9

 received in 2022-11-08, accepted in 2023-01-03,  发布年份 2023

来源: Springer

【 摘 要 】

IntroductionThe COVID-19 pandemic underlined that guidelines and recommendations must be made more accessible and more understandable to the general public to improve health outcomes. The objective of this study is to evaluate, quantify, and compare the public’s understanding, usability, satisfaction, intention to implement, and preference for different ways of presenting COVID-19 health recommendations derived from the COVID-19 Living Map of Recommendations and Gateway to Contextualization (RecMap).Methods and analysisThis is a protocol for a multi-method study. Through an online survey, we will conduct pragmatic allocation-concealed, blinded superiority randomized controlled trials (RCTs) in three populations to test alternative formats of presenting health recommendations: adults, parents, and youth, with at least 240 participants in each population. Prior to initiating the RCT, our interventions will have been refined with relevant stakeholder input. The intervention arm will receive a plain language recommendation (PLR) format while the control arm will receive the corresponding original recommendation format as originally published by the guideline organizations (standard language version). Our primary outcome is understanding, and our secondary outcomes are accessibility and usability, satisfaction, intended behavior, and preference for the recommendation formats. Each population’s results will be analyzed separately. However, we are planning a meta-analysis of the results across populations. At the end of each survey, participants will be invited to participate in an optional one-on-one, virtual semi-structured interview to explore their user experience. All interviews will be transcribed and analyzed using the principles of thematic analysis and a hybrid inductive and deductive approach.Ethics and disseminationThrough Clinical Trials Ontario, the Hamilton Integrated Research Ethics Board has reviewed and approved this protocol (Project ID: 3856). The University of Alberta has approved the parent portion of the trial (Project ID:00114894). Findings from this study will be disseminated through open-access publications in peer-reviewed journals and using social media.Trial registrationClinicaltrials.gov NCT05358990. Registered on May 3, 2022

【 授权许可】

CC BY   
© The Author(s) 2023

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