Taxillus chinensis (DC.) Danser: a comprehensive review on botany, traditional uses, phytochemistry, pharmacology, and toxicology

Chinese Medicine

Review

Chunxiang Zhang¹  Haiyang Hu²  Junzhu Deng²  Wenjun Zou²  Xin Yang³  Jian Liu³  Long Wang³  Anguo Wu³  Yong Tang³  Mi Qin³  Dalian Qin³  Qianqian Huang³  Lu Yu³  Jianming Wu⁴ 

[1] Institute of Cardiovascular Research, the Key Laboratory of Medical Electrophysiology, Ministry of Education of China, Medical Key Laboratory for Drug Discovery and Druggability Evaluation of Sichuan Province, Southwest Medical University, Luzhou, China;School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China;School of Pharmacy, Southwest Medical University, Luzhou, China;School of Pharmacy, Southwest Medical University, Luzhou, China;Institute of Cardiovascular Research, the Key Laboratory of Medical Electrophysiology, Ministry of Education of China, Medical Key Laboratory for Drug Discovery and Druggability Evaluation of Sichuan Province, Southwest Medical University, Luzhou, China;

关键词: Taxillus chinensis;    Botany;    Traditional uses;    Phytochemistry;    Pharmacology;    Toxicology;   

DOI  :  10.1186/s13020-022-00694-5

 received in 2022-08-26, accepted in 2022-11-26,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundTaxillus chinensis (DC.) Danser (T. chinensis), known as “Sangjisheng” in Chinese, is a member of the family Loranthaceae, with the traditional functions of “dispelling wind dampness, strengthening bones and muscles, and preventing miscarriage”. Since Eastern Han dynasty, it has been used for the treatment of rheumatoid arthritis, arthralgia, threatened abortion, and hypertension. Nowadays, T. chinensis is included in the 2020 Edition of the Chinese Pharmacopoeia as Taxilli Herba. The purpose of this review is to summarize the latest research on T. chinensis in recent years, and make critical comments, so as to provide reference for the clinical application and modern research of T. chinensis.Main bodyIn this review, we summarize the botany, traditional uses, and research advances in the phytochemistry and pharmacological effects of T. chinensis. Its toxicity has also been discussed. The published literature on current pharmacological and toxicological data has also been assessed. To date, approximately 110 compounds, including flavonoids, phenolic acids, phenylpropanoids, tannins, glycosides, amino acids, and nucleosides, have been identified in T. chinensis. Flavonoids are considered the most vital bioactive ingredients in T. chinensis. Pharmacological studies have demonstrated that T. chinensis possesses anti-inflammatory, antioxidant, anticancer, antimicrobial, antiviral, diuretic, antihypertensive, antihyperglycemic, and other properties.ConclusionCurrently, research on T. chinensis is in the preliminary stages, and further research is required to understand the active compounds present and mechanisms of action. We hope that this comprehensive review of T. chinensis will serve as a background for further research.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

41408_2022_764_Article_IEq16.gif

41408_2022_764_Article_IEq15.gif

41408_2022_764_Article_IEq14.gif

41408_2022_764_Article_IEq13.gif

41408_2022_764_Article_IEq12.gif

41408_2022_764_Article_IEq11.gif

41408_2022_764_Article_IEq10.gif

41408_2022_764_Article_IEq9.gif

41408_2022_764_Article_IEq8.gif

41408_2022_764_Article_IEq7.gif

41408_2022_764_Article_IEq6.gif

Fig. 2

41408_2022_764_Article_IEq3.gif

Fig. 1

41408_2022_764_Article_IEq1.gif

Fig. 2

Fig. 5

Fig. 1

Fig. 1

40249_2022_1045_Article_IEq27.gif

Fig. 5

40249_2022_1045_Article_IEq25.gif

40249_2022_1045_Article_IEq24.gif

40249_2022_1045_Article_IEq23.gif

40249_2022_1045_Article_IEq22.gif

40249_2022_1045_Article_IEq21.gif

40249_2022_1045_Article_IEq20.gif

40249_2022_1045_Article_IEq17.gif

40249_2022_1045_Article_IEq16.gif

Fig. 1

40249_2022_1045_Article_IEq15.gif

40249_2022_1045_Article_IEq14.gif

40249_2022_1045_Article_IEq13.gif

40249_2022_1045_Article_IEq12.gif

40249_2022_1045_Article_IEq11.gif

40249_2022_1045_Article_IEq10.gif

40249_2022_1045_Article_IEq9.gif

40249_2022_1045_Article_IEq8.gif

40249_2022_1045_Article_IEq7.gif

40249_2022_1045_Article_IEq6.gif

Fig. 1

40249_2022_1045_Article_IEq1.gif

Fig. 4

Fig. 1

Fig. 1

Fig. 4

12864_2022_9026_Article_IEq26.gif

Fig. 3

Fig. 3

Fig. 8

Fig. 2

Fig. 2

Fig. 2

Fig. 1

Fig. 1

Fig. 2

Fig. 6

Fig. 8

Fig. 1

Fig. 2

Fig. 3

Fig. 6

Fig. 2

Fig. 3

Fig. 3

Fig. 3

Fig. 2

Fig. 3

13731_2022_257_Article_IEq12.gif

Fig. 1

13731_2022_257_Article_IEq9.gif

13731_2022_257_Article_IEq7.gif

Fig. 2

Fig. 1

13731_2022_257_Article_IEq4.gif

Fig. 3

13731_2022_257_Article_IEq2.gif

Fig. 3

Fig. 1

Fig. 6

Fig. 5

Fig. 2

Fig. 2

Fig. 5

Fig. 1

Fig. 1

Fig. 1

Fig. 5

40708_2022_178_Article_IEq39.gif

Fig. 5