Associations of environmental factors with total cholesterol level of middle-aged and elderly people in China

BMC Public Health

Research

Congxia Wang¹  Hao Li²  Miao Ge²  Zehua Pei²  Jinwei He³ 

[1] Department of Cardiology, the Second Affiliated Hospital of Medical College, Xi’an Jiaotong University, No. 157, Xiwu Road, 710004, Xi’an, China;Institute of Healthy Geography, School of Geography and Tourism, Shaanxi Normal University, 620 West Chang’an Street, Chang’an District, 710119, Xi’an, China;Medical School, Yan’an University, 580 Shengdi Road, 716000, Yan’an, China;

关键词: Cardiovascular disease;    Total cholesterol level;    Middle-aged and elderly people;    Environmental factors;    GeoDetector;    Geographically weighted regression;   

DOI  :  10.1186/s12889-022-14922-y

 received in 2022-03-28, accepted in 2022-12-21,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundDyslipidemia is a key factor causing cardio cerebrovascular diseases, and the total cholesterol (TC) is an important lipid indicator among them. Studies have shown that environmental factors have a strong association with TC levels. Previous studies only focused on the seasonal variation of TC level and the short-term effects of some environmental factors on TC level over time, and few studies explored the geographical distribution of TC level and quantified the impact of environmental factors in space.MethodsBased on blood test data which was from China Health and Retirement Longitudinal Study (Charls) database, this study selected the TC level test data of middle-aged and elderly people in China in 2011 and 2015, and collected data from 665 meteorological stations and 1496 air pollutant monitoring stations in China. After pretreatment, the spatial distribution map of TC level was prepared and the regional statistics were made. GeoDetector and geographically weighted regression (GWR) were used to measure the relationship between environmental factors and TC level.ResultsThe TC level of middle-aged and elderly in China was higher in females than in males, and higher in urban areas than in rural areas, showing a clustered distribution. The high values were mainly in South China, Southwest China and North China. Temperature, humidity, PM10 and PM2.5 were significant environmental factors affecting TC level of middle-aged and elderly people. The impact of pollutants was more severe in northern China, and TC level in southern China was mainly affected by meteorological factors.ConclusionsThere were gender and urban-rural differences in TC levels among the middle-aged and elderly population in China, showing aggregation in geographical distribution. Meteorological factors and air pollutants may be very important control factors, and their influencing mechanism needs further study.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

Fig. 1

Fig. 2

12864_2022_9026_Article_IEq78.gif

Fig. 1

Fig. 4

Fig. 2

Fig.1