Antifungal activity, mechanical properties, and accuracy of three-dimensionally printed denture base with microencapsulated phytochemicals on varying post-polymerization time

BMC Oral Health

Research

Ji-Hyun Lee¹  Ye-Hyeon Jo¹  Won-Jun Lee²  Hyung-In Yoon² 

[1] Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea;Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, 101, Daehak-ro, Jongno-gu, 03080, Seoul, Republic of Korea;

关键词: 3D printing;    Denture base;    Phytoncide;    Microcapsule;    Antifungal activity;    Post-polymerization time;   

DOI  :  10.1186/s12903-022-02654-9

 received in 2022-07-29, accepted in 2022-12-08,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundStudies on the antifungal activity, flexural strength, Vickers hardness, and intaglio surface trueness of three-dimensionally printed (3DP) denture bases with microencapsulated phytochemicals with respect to changes in post-polymerization time (PPT) are lacking.MethodsSpecimens of various shapes and dimensions were fabricated with a 3DP denture base resin mixed with 5 wt% phytoncide-filled microcapsules. Each specimen was subjected to different PPT protocols of 5, 10, 20, and 30 min. Specimens without microcapsules with 5-min PPT were used as the negative control group. Cell colonies were counted to evaluate antifungal activity. Three-point bending and Vickers hardness tests were performed to measure the flexural strengths and hardness of the specimens. Fourier-transform infrared spectrometry was used to inspect the degree of conversion (DC). The intaglio surface trueness was measured using root-mean-square estimates calculated by superimposition analysis. A non-parametric Kruskal–Wallis test or one-way analysis of variance was performed (α = 0.05).ResultsThe specimens with microcapsules and 10-min PPT showed the highest antifungal activity among the tested groups. Compared with the positive control group (5-min PPT), the specimens with PPTs of 10 min or longer showed significantly higher mean flexural strength, higher DC, greater hardness, and better trueness (all, P < 0.05). Except for the difference in antifungal activity, no statistically significant differences were detected between the specimens subjected to 10-, 20-, and 30-min PPT.ConclusionThe 3DP denture base filled with microencapsulated phytoncide showed different antifungal activity and physical properties on changing PPT. The 3DP denture base containing phytoncide-filled microcapsules at 5 wt% concentration and subjected to 10-min PPT exhibited sufficient antifungal activity as well as mechanical properties and accuracy within clinical acceptance.

【 授权许可】

CC BY   
© The Author(s) 2022

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