Vitamin D serum level in participants with positive history of recurrent herpes labialis

BMC Oral Health

卷:23

Research

Maryam Karandish¹  Zahra Ranjbar²  Fatemeh Lavaee²  Farnaz Peiravian³  Fateme Zarei³ 

[1] Department of Orthodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran;

[2] Oral and Dental Disease Research center, Oral and Maxillofacial Disease Department, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran;

[3] Student research committee, Shiraz University of Medical Sciences, Shiraz, Iran;

关键词: Recurrent herpes labialis;    Vitamin D;    Serum;   

DOI  :  10.1186/s12903-023-02924-0

 received in 2022-10-25, accepted in 2023-03-29,  发布年份 2023

来源: Springer

【 摘 要 】

AimVitamin D plays an important role in immune system regulation, also its deficiency is assumed to affect the patients’ predisposition to viral diseases such as recurrent herpes labialis. In this cross-sectional study, we tried to compare the mean serum level of vitamin D in participants with a positive history of recurrent herpes labial lesions and healthy controls.Materials and methodsThe vitamin D serum level of 43 participants with a positive history of recurrent herpes labial lesions who were referred to the Motahhari laboratory in Shiraz during 2020–2022, was compared with 42 healthy controls. It was assessed by an Elisa kit. An Independent T-test was used to compare the vitamin D serum level between two genders. In order to assess the mean age value and gender distribution, an independent T-test and Pearson Chi-Square were used, respectively for the two groups. The serum vitamin D level was compared between both control and test groups.ResultsThere was no significant difference between vitamin D mean serum levels in the two evaluated groups (p.value = 0.72). Although the age (p.value = 0.09) and recurrence (p.value = 0.13) of herpes labialis had no statistically significant relation to the vitamin D serum level, the healing duration of herpes labialis was inversely related (p.value = 0.01). Lower-level of serum vitamin D were accompanied by a longer healing duration of the lesions.ConclusionAlthough the vitamin D serum level of participants with a history of recurrent herpes labialis had no relation with age and herpes virus recurrence frequency, a longer healing duration of lesions had been reported in patients with lower serum levels of vitamin D.

【 授权许可】

CC BY   
© The Author(s) 2023