Functional parathyroid cyst in a patient with systemic lupus erythematosus: a case report

Endocrinology, Diabetes & Metabolism Case Reports

article

Jingjing Jiang¹  Mei Zhang²  Ronghua He²  Meiping Shen³  Wei Liu² 

[1] Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University;Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University;The First Affiliated Hospital of Nanjing Medical University

关键词: Adult;    Female;    Asian - Chinese;    China;    Parathyroid;    Thyroid;    Parathyroid cyst;    Functional parathyroid cyst;    Systemic lupus erythematosus;    Kidney stones;    Neck mass;    Erythema;    Calcium (serum);    PTH;    Ultrasound scan;    Fine needle aspiration biopsy;    MRI;    Sestamibi scan;    Calcium (urine);    X-ray;    Haemoglobin;    Antinuclear antibody;    C3 complement;    C4 complement;    Hyaluronic acid;    Type 4 collagen;    Type 3 precollagen;    Resection of tumour;    Alendronate;    Bisphosphonates;    Calcium gluconate;    Prednisolone;    Glucocorticoids;    Thalidomide;    Error in diagnosis/pitfalls and caveats;    February;    2015;   

DOI  :  10.1530/EDM-14-0100

学科分类：血液学

来源: Bioscientifica Ltd.

【 摘 要 】

Functional parathyroid cysts are a rare cause of primary hyperparathyroidism and are often mistaken for thyroid cysts.Systemic lupus erythematosus (SLE) is also a very rare cause of hypercalcemia. We report the case of a 62-year-old woman,who was diagnosed with SLE 30 years ago, presenting with clinical and biochemical features of primary hyperparathyroidism.Laboratory investigation revealed increased serum calcium and parathyroid hormone (PTH) levels; neck ultrasonography(USG) revealed 40!34!26 mm cystic mass in the left lobe of thyroid gland. PTH level in the cysts was O2500 pg/ml,determined by USG-guided fine-needle aspiration (FNA). In this case, no evidence for potential pathogenic associationbetween parathyroid cyst and SLE was uncovered. However, the recognition of this association is very important because thetherapeutical strategy is completely different. Operative management is usually straightforward and alleviates symptomsand any biochemical abnormalities caused by the cyst.

【 授权许可】

CC BY-NC-ND