Stereotactic radiosurgery XX: ocular neuromyotonia in association with gamma knife radiosurgery

Endocrinology, Diabetes & Metabolism Case Reports

article

W C Candy Sze¹  Joe McQuillan¹  P Nicholas Plowman¹  Niall MacDougall¹  Philip Blackburn¹  H Ian Sabin¹  Nadeem Ali¹  William M Drake¹ 

[1] St Bartholomew’s Hospital

关键词: Adult;    Female;    Asian - Chinese;    White;    Australia;    Ovaries;    Pituitary;    Thyroid;    Pituitary;    TRH;    TSH;    Progesterone;    FSH;    LH;    Cortisol;    Thyroxine (T4);    Triiodothyronine (T3);    Prolactin;    Oestradiol (E2);    Pituitary hyperplasia;    PCOS;    Hypothyroidism;    Premature ovarian failure;    Ovarian cancer;    Idiopathic pituitary hyperplasia;    Abdominal pain;    Diarrhoea;    Hypothyroidism;    Headache;    Fatigue;    Galactorrhoea;    Weight gain;    Confusion;    Cold intolerance;    Amenorrhoea;    Visual disturbance;    Tinnitus;    MRI;    TSH;    FT4;    FT3;    Thyroid function;    Thyroid antibodies;    Electrocardiogram;    GH;    IGF1;    Prolactin;    Oestradiol (E2);    FSH;    LH;    Cortisol (serum);    Progesterone;    Transsphenoidal surgery;    Thyroxine (T4);    Neurosurgery;    Unique/unexpected symptoms or presentations of a disease;    August;    2015;   

DOI  :  10.1530/EDM-14-0106

学科分类：血液学

来源: Bioscientifica Ltd.

【 摘 要 】

We report three patients who developed symptoms and signs of ocular neuromyotonia (ONM) 3–6 months after receivinggamma knife radiosurgery (GKS) for functioning pituitary tumours. All three patients were complex, requiring multimodality therapy and all had received prior external irradiation to the sellar region. Although direct causality cannot beattributed, the timing of the development of the symptoms would suggest that the GKS played a contributory role in thedevelopment of this rare problem, which we suggest clinicians should be aware of as a potential complication.

【 授权许可】

CC BY-NC-ND