Formulation and Evaluation of Herbal Skin Whitening Cream

American Journal of PharmTech Research

article

Mukati Sandeep¹  Sharma Ayushi¹  Dwivedi Sangeeta¹  Koshta Ashok¹  Joshi Ankur¹  Malviya Sapna¹  Kharia Anil¹ 

[1] Modern Institute of Pharmaceutical Sciences

关键词: Melanocyte;    Epidermis;    Skin;    Melanin;    Lycopene;    Citric acid;    Tocopherol;   

DOI  :  10.5281/zenodo.7407658

学科分类：药学

来源: American Journal Of Pharmtech Research

【 摘 要 】

Melanin is the natural color in our skin is synthesized by melanocytes. The distribution pattern in the nearby keratinocytes and the nature of the formed melanin determine the actual color of our skin. Melanin form through the series of oxidative reaction involving the amino acid tyrosine in the presence of enzyme tyrosinase. Skin whitening agent after inhibit the activity of tyrosinase. The drawback of the quick effect was, the high cytotoxicity of hydroquinone and its huge irritation potential. So that’s why herbal medicines are currently in demand and their popularity is increasing day by day. The objective of this research is to formulate skin whitening formulation, which have ability to give whitening effect without any side effects using herbal products. Now a day’s hyperpigmentation is a major problem. As per previous literature survey it is reported that lycopene, Citric acid & Tocopherol shows significant result in skin whitening activity. It is reported that plants Tomato, Lemon & Cucumber (fruits) contain high amount of Lycopene, Citric acid & Tocopherol. So from above conclusion to hypothesize that this plants may have significant role in skin whitening.

【 授权许可】

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