The stringency of the containment measures in response to COVID-19 inversely correlates with the overall disease occurrence over the epidemic wave

Bratislava Medical Journal

article

Roman MEZENCEV¹  Cyril KLEMENT² 

[1] Georgia Institute of Technology, School of Biological Sciences;Slovak Medical University, Faculty of Public Health

关键词: non-pharmaceutical interventions;    containment;    COVID-19;    mobility;    social distancing;    Containment and Health Index;    epidemiology;    public health measures;    SARS-CoV-2;   

DOI  :  10.4149/BLL_2022_098

学科分类：医学（综合）

来源: AEPress, s.r.o.

【 摘 要 】

Non-pharmaceutical interventions (NPIs) were the only viable choice to mitigate or suppress transmission of COVID-19 in the absence of efficient and safe vaccines. In this study, we examined the association between the stringency of containment measures and cumulative incidence of the COVID-19 cases in the first wave of the pandemic across 28 European countries. Our results support the effectiveness of containment measures in the mitigation or suppression of COVID-19 epidemics. Early adoption of stringent containment measures prior to detection of the first confirmed case, together with ramping up containment stringency during the early days of epidemics, was associated with a lower disease occurrence. The delayed adoption of stringent containment measures did not fully compensate for the lack of early response. Containment measures continue to play a significant role in the control of COVID-19 in the post-vaccination period, when limited vaccination coverage, the emergence of vaccine resistance, and/or increased mobility enabled further disease transmission (Tab. 4, Fig. 22, Ref. 50).

【 授权许可】

CC BY