Ischemic stroke with extensive vasculopathy in a patient with neurofibromatosis type 1

Radiology Case Reports

article

Fiona J. Desmond¹  Alina Buture¹  Eoin C. Kavanagh¹  Sean Murphy¹ 

[1] Department of Radiology, Mater Misericordiae University Hospital

关键词: Neurofibromatosis type 1 (NF1);    Stroke;    Vasculopathy;    Dolichoectasia;    Pseudoaneurysm;    Dissection;   

DOI  :  10.1016/j.radcr.2022.05.029

学科分类：生物化学工程

来源: University of Washington * Department of Radiology

【 摘 要 】

Neurofibromatosis type 1 is an autosomal dominant genetic disorder with multisystem manifestations including vascular abnormalities. The condition is also associated with an increased risk of both ischemic and hemorrhagic stroke. Here we report a case of a 60-year-old male with known neurofibromatosis who presented with right sided hemiparesis . Neuroimaging work-up revealed left internal carotid artery dissection and tandem occlusion of the left internal carotid artery and left middle cerebral artery . There was associated territorial ischemic infarction. The patient was found to have extensive intra and extra cranial vasculopathy including gross basilar dolichoectasia and a right-sided cervical internal carotid artery pseudoaneurysm . This case highlights the clinical significance of neurofibromatosis associated vasculopathy which can result in stroke.

【 授权许可】

CC BY|CC BY-NC-ND