Anlotinib helps alleviate radiation pneumonitis: A case report

Precision Radiation Oncology

article

Jiazhen Chen¹  Cunliang Wang¹  Xudong Hu¹ 

[1] Department of Radiotherapy, Shandong Cancer Hospital and Institute, Shandomg First Medical University ,(Shandong Academy of Medical Sciences)

关键词: anlotinib;    esophageal cancer;    radiation-induced lung injury;    tyrosine kinase inhibitors;   

DOI  :  10.1002/pro6.1139

学科分类：社会科学、人文和艺术（综合）

来源: Wiley

【 摘 要 】

Radiation pneumonitis is a serious side effect of thoracic radiotherapy with no established treatment currently. Anlotinib is a small-molecule tyrosine kinase inhibitor (TKI) with anti-angiogenic effects. The effect of TKIs in the treatment of radiation pneumonitis remains to be elucidated. We investigated whether anlotinib could alleviate radiation pneumonitis. We report a case of a patient with esophageal cancer who received anlotinib for radiation pneumonitis following radiotherapy. We also reviewed related studies to address this issue. The results in this patient suggest that anlotinib may be a valid treatment option for radiation pneumonitis.

【 授权许可】

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