Real-world effectiveness and safety profile of teriflunomide in the management of multiple sclerosis in the Gulf Cooperation Council countries: An expert consensus narrative review

Multiple Sclerosis Journal �C Experimental, Translational and Clinical

article

Raed Alroughani¹  Jihad Inshasi²  Mona Al Khawajah³  Samar Farouk Ahmed⁴  Yaser Al Malik⁶  Jaber Alkhabouri⁹  Ahmed Shatila^1,10  Salman Aljarallah^1,11  Edward J Cupler^1,12  Shireen Al Qureshi^1,13  Mona Thakre^1,14  Heba Elhasin^1,15  Aly Ezzat^1,16  Sherif Roushdy^1,16 

[1] Division of Neurology, Department of Medicine, Al-Amiri Hospital;Neurology Department, Rashid Hospital and Dubai Medical College, Dubai Health Authority;KFSH-R;Ibn Sina Neurology Hospital;Department of Neurology and Psychiatry, Minia University;College of Medicine, King Saud Bin Abdul Aziz University for Health Sciences;King Abdullah International Medical Research Center;Division of Neurology, King Abdul Aziz Medical City, National Guard Health Affairs;Khoula hospital;SSMC Hospital;College of Medicine, King Saud University;King Faisal Specialist Hospital and Research Center;Johns Hopkins Aramco Healthcare;Al Zahraa Hospital;Tawam Hospital;Sanofi Genzyme

关键词: multiple sclerosis;    teriflunomide;    real-world evidence;    relapse;    disease-modifying therapies;   

DOI  :  10.1177/20552173221077185

来源: Sage Journals

【 摘 要 】

Background The prevalence of multiple sclerosis (MS) is increasing in Gulf Cooperation Council (GCC) countries. Multiple sclerosis contributes to significant burden on patients and caregivers. The pharmacological treatment in MS involves treating acute exacerbations and preventing relapses and disability progression using disease-modifying therapies. Clinical evidence suggests that teriflunomide is one of the therapeutic choices for patients with relapsing–remitting MS (RRMS). However, genetic and cultural differences across different regions may contribute to variations in drug use. Therefore, it is necessary to consider real-world evidence for teriflunomide usage in GCC countries.

【 授权许可】

Unknown