Recent Advances in Definitive Radiotherapy for Prostate Cancer

European Medical Journal Oncology

article

Michael Pinkawa¹ 

[1] Department of Radiation Oncology, RWTH Aachen University

关键词: Prostate cancer;    positron emission tomography;    magnetic resonance imaging;    external-beam radiotherapy;    intensity-modulated radiotherapy;    image-guided radiotherapy;    simultaneous integrated boost;    hypofractionation;    dose escalation.;   

DOI  :  10.33590/emjoncol/10310220

学科分类：社会科学、人文和艺术（综合）

来源: European Medical Journal

【 摘 要 】

Definitive radiation therapy is a well-recognised curative treatment option for localised prostate cancer. A suitable technique, dose, target volume, and the option of a combination with androgen deprivation therapy needs to be considered. An optimal standard external beam radiotherapy includes currently the intensity-modulated and image-guided radiotherapy techniques with total doses of ≥76-78 Gy in conventional fractionation. Data from several randomised studies increasingly support the rationale for hypofractionated radiotherapy. A simultaneous integrated boost with dose escalation focused on a computed tomography/positron emission tomography or magnetic resonance imaging/magnetic resonance spectroscopy detected malignant lesion is an option to increase tumour control with potentially no additional toxicity. The application of a spacer is a promising concept for optimal protection of the rectal wall.

【 授权许可】

CC BY-NC