Digital Necrosis as Initial Manifestation of Multiple Myeloma: An Unusual Case Report

European Medical Journal Hematology

article

Hind Zrikem¹  Abderrahim Raissi¹  Salma Amrani Idrissi¹  Hicham Yahyaoui¹  Saloua Abbassi¹  Mustapha Ait Ameur¹  Mohammed Chakour¹ 

[1] Department of Laboratory Hematology, IBN SINA Military Hospital

关键词: Case report;    cryoglobulinemia;    multiple myeloma (MM).;   

DOI  :  10.33590/emjhematol/21-00164

来源: European Medical Journal

【 摘 要 】

Clinical manifestations of multiple myeloma are variable. The authors report a 68-year-old female who presented to the hospital with bilateral digital necrosis and dry gangrenous toes in both left and right feet. She was diagnosed with IgA-λ multiple myeloma associated with Type I cryoglobulinaemia. Emergency management consisted in hyperhydration (plasmapheresis was not available) and thromboprophylaxis. Necrotic digits were amputated. Chemotherapy (bortezomib, lenalidomide, and dexamethasone) was started with good initial evolution. This uncommon presentation can easily be missed, and clinicians should be aware of a possible underlying malignancy.

【 授权许可】

CC BY-NC