An Update on the Treatment of Helicobacter Pylori Infection

European Medical Journal Gastroenterology

article

Sinéad Marian Smith¹ 

[1] Department of Clinical Medicine, School of Medicine;School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin

关键词: Helicobacter pylori;    triple therapy;    bismuth quadruple therapy;    sequential therapy;    concomitant therapy;    hybrid therapy;    antibiotic resistance.;   

DOI  :  10.33590/emjgastroenterol/10310813

学科分类：社会科学、人文和艺术（综合）

来源: European Medical Journal

【 摘 要 】

Helicobacter pylori  treatment is becoming a challenge in light of increasing antimicrobial resistance and falling eradication rates. This is a cause for concern based on the complications of  H. pylori  infection, which include gastric and peptic ulcers, gastric cancer, and mucosa-associated lymphoid tissue lymphoma. This review discusses recent data assessing the current treatment options for  H. pylori  infection and the importance of considering the prevalence of antibiotic resistance at a regional level when choosing an appropriate therapy. Alternatives to the standard first-line treatment, such as bismuth and non-bismuth quadruple therapies, are outlined and rescue therapies involving levofloxacin and rifabutin are also reviewed.

【 授权许可】

CC BY-NC