Burden of Aortic Aneurysm and Its Attributable Risk Factors from 1990 to 2019: An Analysis of the Global Burden of Disease Study 2019

Frontiers in Cardiovascular Medicine

article

Zhuo Wang¹  Yayu You¹  Zhehui Yin¹  Qinyi Bao¹  Shuxin Lei¹  Jiaye Yu¹  Cuiping Xie¹  Feiming Ye¹  Xiaojie Xie¹ 

[1] Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine;International Institutes of Medicine, The Fourth Affiliated Hospital, Zhejiang University School of Medicine

关键词: aortic aneurysm;    Global Burden of Diseases Study;    systematic analysis;    mortality;    disability-adjusted life year (DALY);   

DOI  :  10.3389/fcvm.2022.901225

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Background Global and national estimates on the epidemiology of aortic aneurysms are prerequisites for disease management and policymaking. Based on the Global Burden of Disease (GBD) 2019, this study aimed to discern the global aortic aneurysm burden by systematically analyzing demographic data on mortality and exploring the attributable risks and relevant factors. Methods The data analyzed in this study were available in the Global Health Data Exchange (GHDx) online query tool. The population in our study comprised individuals from 204 countries and territories from 1990 to 2019. The estimated annual percentage changes (EAPCs) were performed to assess the temporal trends of aortic aneurysms and their attributable risks. Spearman correlation analysis was performed to explore the relationship between the burden of aortic aneurysm and covariates. Results Although aortic aneurysm-related deaths (82.1%) and disability-adjusted life years (DALYs) (67%) increased from 1990 to 2019, the global trend of age-standardized rate of death (ASRD) (EAPC: −1.34, 95% CI = −1.46 to −1.22, P 0.05), and alcohol consumption (male: R = 0.46, P < 0.001; female: R = 0.42, P < 0.001) had a positive correlation with ASRM. Besides, standard of living and medical resources positively related to burden of aortic aneurysm. Conclusion In this study, a decreasing trend of aortic aneurysm burden was found globally, especially in advanced regions. Aged men who smoke and women who have hypertension should pay close attention to, particularly in deprived economic groups, and many approaches can be performed to reduce the burden of aortic aneurysms.

【 授权许可】

CC BY