Cardiovascular Complications of COVID-19 Vaccines

Frontiers in Cardiovascular Medicine

article

Runyu Liu¹  Junbing Pan¹  Chunxiang Zhang²  Xiaolei Sun¹ 

[1] Department of General Surgery ,(Vascular Surgery), The Affiliated Hospital of Southwest Medical University;Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University;Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou;Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University;Department of Interventional Medicine, The Affiliated Hospital of Southwest Medical University;King's College London British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, Faculty of Life Science and Medicine, King's College London

关键词: COVID-19;    vaccine;    cardiovascular;    complication;    mRNA;   

DOI  :  10.3389/fcvm.2022.840929

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Coronavirus disease 2019 (COVID-19) has become a global public health catastrophe. Vaccination against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is proven to be the most effective measure to suppress the pandemic. With the widespread application of the four vaccines, namely, ChAdOx1, Ad26.COV2.S, BNT162b2, and mRNA-1273.2, several adverse effects have been reported. The most serious type of complication is cardiovascularly related, including myocarditis, immune thrombocytopenia (ITP), cerebral sinus venous thrombosis, among others. All these adverse events undermine the health of the vaccinees and affect the administration of the vaccines. As the distribution of COVID-19 vaccines is surrounded by suspicion and rumors, it is essential to provide the public with accurate reports from trusted experts and journals. Monitoring the safety of COVID-19 vaccines is an important and ongoing process that is also urgent. Thus, we summarized the cardiovascular complications of the major types of COVID-19 vaccines, including mRNA vaccines, which are now generally considered to be innovative vaccines, and the future for vaccination against COVID-19, in addition to the underlying pathogenesis and potential therapeutics.

【 授权许可】

CC BY