An Intelligent Diagnostic System for Thyroid-Associated Ophthalmopathy Based on Facial Images

Frontiers in Medicine

article

Xiao Huang¹  Lie Ju²  Jian Li¹  Linfeng He¹  Fei Tong¹  Siyu Liu¹  Pan Li¹  Yun Zhang¹  Xin Wang²  Zhiwen Yang²  Jianhao Xiong²  Lin Wang²  Xin Zhao²  Wanji He²  Yelin Huang²  Zongyuan Ge²  Xuan Yao²  Weihua Yang⁵  Ruili Wei¹ 

[1] Department of Ophthalmology, Changzheng Hospital, Naval Medical University;Airdoc LLC;Faculty of Engineering, Monash University;Department of Ophthalmology, Naval Medical Center of the People’s Liberation Army, Naval Medical University;The Laboratory of Artificial Intelligence and Bigdata in Ophthalmology, The Affiliated Eye Hospital of Nanjing Medical University

关键词: artificial intelligence;    diagnosis;    facial images;    machine learning;    medical data analysis;    thyroid-associated ophthalmopathy;   

DOI  :  10.3389/fmed.2022.920716

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background Thyroid-associated ophthalmopathy (TAO) is one of the most common orbital diseases that seriously threatens visual function and significantly affects patients’ appearances, rendering them unable to work. This study established an intelligent diagnostic system for TAO based on facial images. Methods Patient images and data were obtained from medical records of patients with TAO who visited Shanghai Changzheng Hospital from 2013 to 2018. Eyelid retraction, ocular dyskinesia, conjunctival congestion, and other signs were noted on the images. Patients were classified according to the types, stages, and grades of TAO based on the diagnostic criteria. The diagnostic system consisted of multiple task-specific models. Results The intelligent diagnostic system accurately diagnosed TAO in three stages. The built-in models pre-processed the facial images and diagnosed multiple TAO signs, with average areas under the receiver operating characteristic curves exceeding 0.85 (F1 score >0.80). Conclusion The intelligent diagnostic system introduced in this study accurately identified several common signs of TAO.

【 授权许可】

CC BY