Bibliometric Analysis of Cathepsin B Research From 2011 to 2021

Frontiers in Medicine

article

Xiaoli Yang¹  Hua Yin¹  Deyu Zhang²  Lisi Peng²  Keliang Li³  Fang Cui²  Chuanchao Xia²  Zhaoshen Li²  Haojie Huang² 

[1] Department of Gastroenterology, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan;Department of Gastroenterology, Changhai Hospital, Navy/Second Military Medical University;Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University

关键词: cathepsin B;    pancreatic diseases;    Research Frontier;    bibliometrics;    visualization;   

DOI  :  10.3389/fmed.2022.898455

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Cathepsin B (CTSB) is a lysosomal protease implicated in the progression of various diseases. A large number of CTSB-related studies have been conducted to date. However, there is no comprehensive bibliometric analysis on this subject. In our study, we performed quantitative analysis of CTSB-related publications retrieved from the Science Citation Index Expanded (SCIE) of the Web of Science Core Collection (reference period: 2011–2021). A total of 3,062 original articles and reviews were retrieved. The largest number of publications were from USA ( n = 847, 27.66%). The research output of each country showed positive correlation with gross domestic product (GDP) ( r = 0.9745, P < 0.0001). Active collaborations between countries/regions were also observed. Reinheckel T and Sloane BF were perhaps the most impactful researchers in the research landscape of CTSB. Plos ONE was the most prevalent (119/3,062, 3.89%) and cited journal (3,021 citations). Comprehensive analysis of the top citations, co-citations, and keywords was performed to acquire the theoretical basis and hotspots of CTSB-related research. The main topics included CTSB-related cancers and inflammatory diseases, CTSB-associated cell death pattern, and the applications of CTSB. These results provide comprehensive insights into the current status of global CTSB-related research especially in pancreas, which is worthy of continued follow-up by practitioners and clinicians in this field.

【 授权许可】

CC BY