Incidence Trends of Five Common Sexually Transmitted Infections Excluding HIV From 1990 to 2019 at the Global, Regional, and National Levels: Results From the Global Burden of Disease Study 2019

Frontiers in Medicine

article

Leiwen Fu¹  Yinghui Sun¹  Min Han²  Bingyi Wang¹  Fei Xiao³  Yiguo Zhou¹  Yanxiao Gao¹  Thomas Fitzpatrick⁴  Tanwei Yuan¹  Peiyang Li¹  Yuewei Zhan¹  Yong Lu⁵  Ganfeng Luo¹  Junyi Duan⁶  Zhongsi Hong³  Christopher K. Fairley⁷  Tong Zhang⁶  Jin Zhao⁹  Huachun Zou¹ 

[1] School of Public Health ,(Shenzhen), Sun Yat-sen University;Department of Medical Administration, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences;The Fifth Affiliated Hospital of Sun Yat-sen University;Department of Internal Medicine, University of Washington;School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University;Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University;Central Clinical School, Monash University;Melbourne Sexual Health Centre, Alfred Health;Department of HIV/AIDS Control and Prevention, Shenzhen Center for Disease Control and Prevention;Kirby Institute, University of New South Wales

关键词: global burden;    STIs;    syphilis;    chlamydia;    gonorrhea;    trichomoniasis;    genital herpes;   

DOI  :  10.3389/fmed.2022.851635

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective Sexually transmitted infections (STIs) are common worldwide and pose a challenge to public health. We conducted this study to assess the annual incidence of five common STIs, including syphilis, chlamydia, gonorrhea, trichomoniasis, and genital herpes at the global, regional, and national levels. Materials and Methods We obtained detailed data on STIs excluding HIV from 1990 to 2019 from the Global Burden of Disease (GBD) 2019 database. Estimated annual percentage change (EAPC) was calculated to quantify trends in age-standardized incidence rates (ASR) of STIs, stratified by gender, sociodemographic index (SDI) region, and pathogenic microorganism. Results Globally, incident cases of STIs increased by 58.15% from 486.77 million in 1990 to 769.85 million in 2019, but the annual change in ASR was only −0.04% (95% CI −0.09 to 0.01) per year. EAPC was 0.16 (0.06 to 0.26) for syphilis, 0.09 (0.05 to 0.13) for genital herpes, 0.06 (0.03 to 0.09) for trichomoniasis, −0.21 (−0.36 to −0.06) for chlamydia, and −0.14 (−0.19 to −0.08) for gonorrhea. High SDI regions reported significant increases in ASR of syphilis and chlamydia. Conclusions The burden of disease from STIs remains large, though control of STIs has contributed to the decreasing incidence in most regions, especially in the low-SDI regions. Globally, over the past 20 years, the ASR has remained stable for trichomoniasis and genital herpes decreased for chlamydia and gonorrhea, and increased for syphilis.

【 授权许可】

CC BY