Role of GeneXpert or CBNAAT in Diagnosing Tuberculosis: Present Scenario

Medical Journal of Dr. D.Y. Patil Vidyapeeth

article

Garg, Archana¹  Agarwal, Lakshmi²  Mathur, Rishab¹ 

[1] Departments of Microbiology, Government Medical College;Department of Pathology, Government Medical College

关键词: Conventional test;    GeneXpert;    global burden;    multidrug resistance;   

DOI  :  10.4103/mjdrdypu.mjdrdypu_182_20

学科分类：社会科学、人文和艺术（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

About a quarter of the world's population is infected with tuberculosis (TB), with new infection occurring every second. The global burden, particularly with multidrug resistance, is also increasing simultaneously and has become a major health challenge. Earlier and improved case detection, including smear-negative disease, often associated with HIV co-infection, and expanded capacity to diagnose multidrug-resistant TB are global priorities for TB control. Conventional laboratory methods are slow and cumbersome. Hence, novel technologies for rapid detection are the focus of TB research and development. GeneXpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) is one of them, currently unique in its simplification of molecular testing with amplification and detection based on real-time polymerase chain reaction. Xpert MTB/RIF detects MTB as well as RIF resistance directly from sputum within 2 h. This article focuses on the significance of new diagnostic test for TB.

【 授权许可】

CC BY-NC-SA