Association Between Red Blood Cell Distribution Width and COVID-19 Severity in Delta Variant SARS-CoV-2 Infection

Frontiers in Medicine

article

Jianguo Zhang¹  Jianhui Hu²  Xing Huang³  Shixiang Fu⁴  Daoyin Ding⁵  Zhimin Tao¹ 

[1] Department of Emergency Medicine, The Affiliated Hospital of Jiangsu University;Department of Laboratory Medicine, Zhenjiang Hospital Affiliated to Nanjing University of Chinese Medicine, Zhenjiang Hospital of Traditional Chinese Medicine;Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University;Department of Hepatology, The Third People's Hospital of Yangzhou City;Department of Critical Care Medicine, The First People's Hospital of Jiangxia District;Jiangsu Province Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University

关键词: COVID-19;    SARS-CoV-2;    delta variant;    red blood cell distribution width;    vaccination;   

DOI  :  10.3389/fmed.2022.837411

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Studies have discovered that wild-type SARS-CoV-2 infections are commonly linked to abnormalities in the hematological profiles of COVID-19 patients, one such abnormality being characterized by elevations in red blood cell distribution width (RDW). Whether this linkage reoccurs in delta variant SARS-CoV-2 infection remains unexamined. Here we compared baseline blood parameters in COVID-19 patients infected by wild type and its delta variant, respectively. Our results here point to that although the delta variant has shown increased virulence, transmissibility, and vaccine escape, it has a minimally negative impact on RDW values that were previously found prognostic for COVID-19 severity.

【 授权许可】

CC BY