The Use of Clinical Scores in the Management of Immune Thrombocytopenic Purpura in Children

Frontiers in Pediatrics

article

Vasile Eduard Roşu¹  Elena-Lia Spoială¹  Tamara Solange Roşu¹  Anca-Viorica Ivanov¹  Adriana Mocanu¹  Alecsandra Munteanu³  Vasile Valeriu Lupu¹  Ingrith Miron¹  Cristina Gavrilovici¹ 

[1] Department of Mother and Child, “Grigore. T. Popa” University of Medicine and Pharmacy of Iaşi;Sf.Maria Emergency Hospital for Children;Department of Nursing, “Grigore. T. Popa"” University of Medicine and Pharmacy of Iaşi

关键词: immune thrombocytopenic purpura;    children;    bleeding score;    predictive score;    platelet;    risk factors;    diagnostics;   

DOI  :  10.3389/fped.2022.870064

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

While the majority of children with recently diagnosed ITP have a benign, self-limiting condition, most often with a spontaneously recovery, 40% of children with ITP progress toward persistent ITP and 10–20% goes toward chronicity. Several clinical scores have been developed with the aim to perform a better monitoring outcome or to differentiate transient vs. persistent ITP (e.g., Donato score). Our paper aims to describe and to compare the most important scores used in the management of ITP in children: bleeding severity scores and chronicity prediction scores. These scores include a combination of different already known risk factors: age, gender, presence of a previous infections or vaccination, bleeding grade, type of onset, platelet count at diagnosis. The real utility of these scores has been a matter of debate and no consensus has been reached so far as to their necessity to be implemented as compulsory tool in the care of children with ITP.

【 授权许可】

CC BY