Cannabis Use Increases the Risk of Sickness Absence: Longitudinal Analyses From the CONSTANCES Cohort

Frontiers in Public Health

article

Amélia Déguilhem¹  Annette Leclerc¹  Marcel Goldberg¹  Cédric Lemogne²  Yves Roquelaure³  Marie Zins¹  Guillaume Airagnes⁴ 

[1] INSERM;Université Paris Cité, AP-HP, Hôpital Hôtel-Dieu, DMU Psychiatrie et Addictologie, Service de Psychiatrie de l'adulte, INSERM, Institute of Psychiatry and Neuroscience of Paris;Centre Hospitalier Universitaire d'Angers, Pathologie Professionnelle et Médecine du Travail, Research Institute for Environmental and Occupational Health, INSERM, Ester, Epidemiology in Occupational Health and Ergonomics;Université Paris Cité, AP-HP, Hôpital Européen Georges Pompidou, DMU Psychiatrie et Addictologie, Centre Ambulatoire d'Addictologie

关键词: cannabis;    sickness absence;    sick leave;    occupational health;    work;   

DOI  :  10.3389/fpubh.2022.869051

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Aims To examine the longitudinal associations between cannabis use and risks of short (28 days) sickness absences at one-year follow-up. Methods 87,273 participants aged 18-65 years from the French CONSTANCES cohort reported their frequency of cannabis use at inclusion between 2012 and 2018. Sickness absences occurring during one year of follow-up were collected from national medico-administrative registries. Multivariable generalized linear regressions were used to compute the Odds Ratios (OR) with their 95% Confidence Intervals (CI) of having at least one sickness absence at follow-up compared to no sickness absence, while controlling for sociodemographic factors, chronic conditions and occupational factors. Results Cannabis use more than once a month was associated with an increased risk of short (OR, [95% CI]: 1.56 [1.32–1.83]) and medium (1.29 [1.07–1.54]) sickness absences at one-year follow-up, with dose-dependent relationships for short sickness absences (1.13 [1.08–1.18], p -for-trend <0.001). In stratified analyses, cannabis use was associated with an increased risk of sickness absences in older individuals, men, participants with good self-rated health, living or having lived as a couple, and having an open-ended contract. Conclusions Cannabis use prospectively increased the risk of short and medium sickness absences, even from once a month and with a dose-dependent relationship for short sickness absences. These findings should be considered in information and prevention public health campaigns to alert the general population and workers to this increased risk.

【 授权许可】

CC BY