Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine

Case Report

Marika Bajc¹  Fredrik Hedeer¹  Elin Trägårdh²  Ari Lindqvist³ 

[1] Department of Clinical Physiology and Nuclear Medicine, Skåne University Hospital Lund, 22185, Lund, Sweden;Department of Clinical Physiology and Nuclear Medicine, Skåne University Hospital Malmö, Lund University, Lund, Sweden;Research Unit of Pulmonary Diseases, Clinical Research Institute HUCH Ltd., Helsinki University Hospital HUS and Helsinki University, Helsinki, Finland;

关键词: Ventilation;    perfusion;    SPECT;    SARS-CoV-2;    pulmonary embolism;    COVID-19;   

DOI  :  10.1177/11795484211030159

 received in 2021-01-03, accepted in 2021-06-14,  发布年份 2021

来源: Sage Journals

【 摘 要 】

V/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary vasculature, detect the reversed mismatch of poor ventilation and better preserved perfusion (shunt perfusion) in bilateral pulmonary inflammation and indicate redistribution of lung perfusion (antigravitational hyperperfusion) due to cardiac congestion. V/P mismatch and reversed mismatch may be extensive enough to diminish dramatically preserved matching ventilation/perfusion and to induce severe hypoxemia in COVID-19.

【 授权许可】

CC BY   
© The Author(s) 2021

【 图 表 】

Figure 3.