Interrelationship between Asthma and Functional Bowel Disease

European Journal of Inflammation

Clinical Inflammation

N. Verna¹  S. Comani²  G. Riccioni³  M.L. Castellani⁴  C. Petrarca⁴  F. Romano⁵  N. D'Orazio⁵  C. Di Ilio⁵  T. Staniscia⁵  M. A. De Lutiis⁶  R. Della Vecchia⁷ 

[1] Allergology Division, Chieti, Italy;Department of Clinical Science and Bioimaging, University “G. D'Annunzio” Chieti, Italy;Graziano Riccioni, MD, Section of Human Nutrition, Department of Biomedical Science, University “G. D'Annunzio” Chieti, Italy, Tel & Fax ++39.0871.355.6705, e-mail: ;Immunology Division, University “G. D'Annunzio” Chieti, Italy;Section of Epidemiology and Public Health, Chieti, Italy;Section of Human Nutrition, Chieti, Italy;Department of Internal Medicine and Aging, Chieti, Italy;

关键词: asthma;    bronchial hyperresponsiveness;    irritable bowel syndrome;    intestinal motility;    methacholine;    stress;   

DOI  :  10.1177/1721727X0400200305

 received in 2004-03-03, accepted in 2004-07-23,  发布年份 2004

来源: Sage Journals

【 摘 要 】

Gastrointestinal abnormalities have been reported in subjects with bronchial asthma. The aim of this study was to evaluate the presence of irritable bowel syndrome (IBS) in subjects with bronchial asthma. 380 asthmatic patients were selected for body mass index (BMI), sex, and age, before undergoing both methacholine challenge test (MCHt) and skin prick tests. 195 asthmatic patients (51.3%) were positive to MCHt, while 185 (41.6 %) were negative. We also found that 17 (8.7%) of the 276 patients with positive MCHt, and 22 (11.8%) of the 185 patients with negative MCHt were affected by IBS. Therefore, there was no statistical significance between positive MCHt tests and IBS. The results do not demonstrate an interrelationship between asthma and IBS.

【 授权许可】

Unknown   
© 2004 SAGE Publications