Section 2. Exercise-Induced Bronchospasm: Albuterol versus Montelukast: Highlights of the Asthma Summit 2009: Beyond the Guidelines

World Allergy Organization Journal

William J Calhoun²  Gene Colice¹ 

[1] Pulmonary, Critical Care and Respiratory Services, Washington Hospital Center, Professor of Medicine, The George Washington University School of Medicine, Washington, DC;Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX

关键词: montelukast;    albuterol;    bronchial hyperresponsiveness;    airway hyperreactivity;    exercise-induced asthma;    exercise-induced bronchospasm;    asthma;   

Others  :  1180799
DOI  :  10.1097/WOX.0b013e3181d25eac

【 摘 要 】

Exercise-induced bronchospasm (EIB) involves airway obstruction with an onset shortly after exercising. It can occur in individuals without a diagnosis of asthma, but is most common in asthmatic patients (and in this scenario may be referred to as exercise-induced asthma, EIA), correlating with the patient's degree of airway hyperreactivity. While albuterol is the most commonly used rescue and prophylactic medication for EIB, the leukotriene antagonist, monetlukast, may be an appropriate choice for some patients. Clinical data have shown that once-daily treatment with montelukast (5 or 10 mg tablet) can offer protection against EIB within 3 days for some patients. Such an approach might be preferred for patients who have difficulty with inhaled medications and for children who cannot access their inhalers during the school day. Montelukast also may be an option to reduce side effects associated with albuterol for individuals who exercise regularly.

【 授权许可】

   
2010 World Allergy Organization; licensee BioMed Central Ltd.

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