Eosinophilic Dermatosis Associated with Haematological Malignancies: A Report of Two Cases

European Journal of Inflammation

Letter to the Editor

A. Narcisi¹  D. Orsini¹  C. Abruzzese¹  P.P. Di Russo¹  M. Carlesimo¹  G. La Verde²  M.C. Cox² 

[1] U.O.C. Dermatology, II Unit University of Rome “Sapienza”, Rome, Italy;U.O.C. Hematology, II Unit University of Rome “Sapienza ”, Rome, Italy;

关键词: eosinophilic dermatosis;    insect bite-like reaction;    haematological malignancies;   

DOI  :  10.1177/1721727X1201000212

 received in 2011-12-17, accepted in 2012-04-02,  发布年份 2012

来源: Sage Journals

【 摘 要 】

Hematologic malignancies can be associated to dermatological manifestations, with two possible etiopathogenetic mechanisms: a direct invasion of skin by neoplastic cells or a paraneoplastic phenomenon. The eosinophilic dermatosis can be included in the latter class and arc a group of polymorphous dermatitis, clinically characterized by papules, plaques, nodules or vescico-bullous lesions, mainly involving sun-exposure sites. Clinical pictures are similar to an insect bite reaction, but in most cases the patients deny any arthropod contacts. Therefore, they arc now considered as a hypersensitive reaction to different stimuli induced by lymphoproliferative malignancies and the associated immune-deficient state. Herein, we describe two cases of patients affected by a non-Hodgkin lymphoma (NHL), in whom a diagnosis of insect bite-like reaction (IBLR) was made.

【 授权许可】

Unknown   
© 2012 SAGE Publications