Long term persistence of coronavirus SARS-CoV-2 infection

Einstein (São Paulo)

关键词: COVID-19;    SARS-CoV-2;    Infecções Coronavírus;    Coronavírus;   

DOI  :  10.31744/einstein_journal/2021rc6369

来源: DOAJ

【 摘 要 】

ABSTRACT During the COVID-19 pandemic, a case of a long-term persistence of SARS-CoV-2 infection (from March 26 to May 20, 2020) was identified at a private hospital in São Paulo, SP, Brazil. The long-term positivity for SARS-CoV-2 in reverse transcriptase polymerase chain reaction tests of a patient diagnosed with COVID-19 suggests, at least part of patients who recovered, may still carry and transmit the SARS-CoV-2 virus. This fact emphasizes the importance of having at least two negative reverse transcriptase polymerase chain reaction test results for SARS-CoV-2. Serological assays were not particularly helpful in the case described, since the patient had very low antibodies titers at the end of the follow-up period. Low viral loads may not be detected by current molecular methods, leading to wrong conclusions regarding viral clearance.

【 授权许可】

Unknown