Tenth International Foamy Virus Conference2014–Achievements and Perspectives

Viruses

Jacek Kuźmak¹  Marzena Rola–Łuszczak¹  Piotr Kubiś¹  Magdalena Materniak¹  Martin Löchelt²  Dirk Lindemann³  Arifa S. Khan⁴  Florence Buseyne⁵ 

[1] Department of Biochemistry, National Veterinary Research Institute, 24-100 Pulawy, Poland;Department of Genome Modifications and Carcinogenesis, German Cancer Research Center,69121 Heidelberg, Germany;Institute of Virology, Medical Faculty "Carl Gustav Carus", Technische Universität Dresden,01307 Dresden, Germany;Laboratory of Retroviruses, Division of Viral Products, OVRR, CBER, U.S. Food and DrugAdministration, Silver Spring, MD 20993, USA;Unité d'épidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur, 75015 Paris, France;

关键词: foamy viruses;    infection;    zoonotic potential;    restriction factors;    replication;    assembly;    FV vectors;   

DOI  :  10.3390/v7041651

来源: DOAJ

【 摘 要 】

For the past two decades, scientists from around the world, working on different aspects of foamy virus (FV) research, have gathered in different research institutions almost every two years to present their recent results in formal talks, to discuss their ongoing studies informally, and to initiate fruitful collaborations. In this report we review the 2014 anniversary conference to share the meeting summary with the virology community and hope to arouse interest by other researchers to join this exciting field. The topics covered included epidemiology, virus molecular biology, and immunology of FV infection in non-human primates, cattle, and humans with zoonotic FV infections, as well as recent findings on endogenous FVs. Several topics focused on virus replication and interactions between viral and cellular proteins. Use of FV in biomedical research was highlighted with presentations on using FV vectors for gene therapy and FV proteins as scaffold for vaccine antigen presentation. On behalf of the FV community, this report also includes a short tribute to commemorate Prof. Axel Rethwilm, one of the leading experts in the field of retrovirology and foamy viruses, who passed away 29 July 2014.

【 授权许可】

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