Feasibility of a break-in period of less than 24 hours for urgent start peritoneal dialysis: a multicenter study

Renal Failure

Xueyan Zhu¹  Xiaoxuan Zhang²  Liming Yang³  Xi Wen⁴  Wenpeng Cui⁴  Shichen Liu⁴  Xiaoqing Hu⁴  Ping Luo⁴  Wenhua Zhou⁴  Zhanshan Sun⁵ 

[1]Division of Nephrology, Jilin City Central Hospital, Jilin, China

[2]Division of Nephrology, Jilin FAW General Hospital, Changchun, China

[3]Division of Nephrology, The First Hospital of Jilin University-the Eastern Division, Changchun, China

[4]Division of Nephrology, The Second Hospital of Jilin University, Changchun, China

[5]Division of Nephrology, Xing’anmeng people’s Hospital, Ulan Hot, China

关键词: Urgent start peritoneal dialysis;    peritoneal dialysis;    break-in period;    complications;    technique failure;   

DOI  :  10.1080/0886022X.2022.2049306

来源: DOAJ

【 摘 要 】

Purpose Urgent start peritoneal dialysis (USPD) is an effective therapeutic method for end-stage renal disease (ESRD). However, whether it is safe to initiate peritoneal dialysis (PD) within 24 h unclear. We examined the short-term outcomes of a break-in period (BI) of 24 h for patients undergoing USPD.Methods This real-world, multicenter, retrospective cohort study evaluated USPD patients from five centers from January 2013 to August 2020. Patients were divided into BI ≤ 24 h or BI > 24 h groups. The Primary outcomes included incidence of mechanical and infectious complications. The secondary outcome was technique failure. Moreover, we presented a subgroup analysis for patients who did not receive temporary hemodialysis (HD).Results A total of 871 USPD patients were included: 470 in the BI ≤ 24 h and 401 in the BI > 24 h groups. Mechanical and infectious complications did not differ between the two groups across the follow-up timepoints (2 weeks, 1 month, 3 months, and 6 months) (p > 0.05). Multiple logistic regression analysis revealed that BI ≤ 24 h was not an independent risk factor for mechanical complications, catheter migration, or infectious complications (p > 0.05). A BI ≤ 24 h was not an independent significant risk factor for technique failure by multivariate Cox regression analysis (p > 0.05). The subgroup analysis of patients who did not receive temporary HD returned the same results.Conclusion Initiating PD within 24 h of catheter insertion was not associated with increased mechanical complications, infectious complications, or technique failures.

【 授权许可】

Unknown