Does T1- and diffusion-weighted magnetic resonance imaging give value-added than bone scintigraphy in the follow-up of vertebral metastasis of prostate cancer?

Investigative and Clinical Urology

Hee Suk Jung¹  Sung-Woo Park¹  Jong Kil Nam¹  Moon Kee Chung¹  Seong Jang Kim¹  Dong Hoon Lee¹ 

[1] Pusan National University Yangsan Hospital;

关键词: Magnetic resonance imaging;    Neoplasm metastasis;    Prostatic neoplasms;    Spine;   

DOI  :  10.4111/icu.2017.58.5.324

来源: DOAJ

【 摘 要 】

Purpose: To evaluate the effectiveness of limited Magnetic Resonance (MR) images including T1- and diffusion-weighted image (DWI) for monitoring vertebral metastasis in patients with prostate cancer.Materials and Methods: From July 2014 to November 2016, patients diagnosed with spinal metastasis from prostate cancer using 99mTc bone scintigraphy were enrolled. Regardless of the primary local therapy, the changes in spinal metastasis were followed up using bone scan and biparametric MR (T1+DWI). All tests were followed up for more than 3 months.Results: Among the 14 follow-ups of 10 patients, 6 and 10 (including all progressed cases on bone scan) follow-ups were deter-mined to show progressive disease using bone scan and biparametric MR, respectively. Otherwise, we could have predicted neu-rologic sequela earlier using biparametric MR. Examination time for biparametric MR was 15 minutes, and it was 4 hours for bone scan, respectively.Conclusions: Although bone scan has been considered the standard test for bony metastasis in men with prostate cancer, limited MR including T1 and DWI has an additional benefit in monitoring spinal metastasis in patients who are already diagnosed as hav-ing spinal metastasis. The limited MR is more sensitive in detecting progressive disease. In addition, it can reduce neurologic com-plications caused by spinal metastasis.

【 授权许可】

Unknown