Advances in mRNA Vaccines for Infectious Diseases

Frontiers in Immunology

Cuiling Zhang¹  Hu Shan¹  Junwei Li¹  Giulietta Maruggi² 

[1] College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China;GSK, Rockville, MD, United States;

关键词: mRNA vaccine;    infectious disease;    delivery;    mechanism;    application;   

DOI  :  10.3389/fimmu.2019.00594

来源: DOAJ

【 摘 要 】

During the last two decades, there has been broad interest in RNA-based technologies for the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have shown that mRNA vaccines provide a safe and long-lasting immune response in animal models and humans. In this review, we summarize current research progress on mRNA vaccines, which have the potential to be quick-manufactured and to become powerful tools against infectious disease and we highlight the bright future of their design and applications.

【 授权许可】

Unknown