The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration

International Journal of Molecular Sciences

TristynL. Clarke¹  RobertL. Carlone¹  RachaelL. Johnson¹  JonathanJ. Simone¹ 

[1] Department of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1,, Canada;

关键词: AEA;    2-AG;    CB1;    CB2;    endocannabinoid;    regeneration;   

DOI  :  10.3390/ijms22042103

来源: DOAJ

【 摘 要 】

Cannabis has long been used for its medicinal and psychoactive properties. With the relatively new adoption of formal medicinal cannabis regulations worldwide, the study of cannabinoids, both endogenous and exogenous, has similarly flourished in more recent decades. In particular, research investigating the role of cannabinoids in regeneration and neurodevelopment has yielded promising results in vertebrate models. However, regeneration-competent vertebrates are few, whereas a myriad of invertebrate species have been established as superb models for regeneration. As such, this review aims to provide a comprehensive summary of the endocannabinoid system, with a focus on current advances in the area of endocannabinoid system contributions to invertebrate neurodevelopment and regeneration.

【 授权许可】

Unknown