Cetirizine use in childhood: an update of a friendly 30-year drug

Clinical and Molecular Allergy

Giorgio Ciprandi¹  Giuseppe Fabio Parisi²  Salvatore Leonardi²  Amelia Licari³  Gian Luigi Marseglia³  Michele Miraglia del Giudice⁴  Angelo Corsico⁵  Diego Peroni⁶  Carmelo Salpietro⁷ 

[1] Allergy Clinic, Casa di Cura Villa Montallegro;Department of Clinical and Experimental Medicine, University of Catania;Department of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia;Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi Vanvitelli;Pulmonology Clinic, Foundation IRCCS Policlinico San Matteo, University of Pavia;U.O. Pediatria, Azienda Ospedaliero-Universitaria Pisana, Scuola di Specializzazione in Pediatria, University of Pisa;Unit of Pediatric Genetics and Immunology, Department of Pediatrics, University of Messina;

关键词: Cetirizine;    Antihistamines;    Histamine;    H1 receptors;    Children;    Adolescents;   

DOI  :  10.1186/s12948-020-00118-5

来源: DOAJ

【 摘 要 】

Abstract Cetirizine is a second-generation antihistamine, derived from the metabolism of hydroxyzine, highly specific for the H1 receptors, and with marked antiallergic properties. Although its history began more than 30 years ago, it remains one of the most used drugs in children with a leading role in the medical care of children with allergic diseases. Cetirizine use is licensed for paediatric patients for the treatment of allergic rhinitis, and chronic spontaneous urticaria, in Europe in children older than 2 years old and in the USA in children older than 6 months old. This review provides a practical update on the use of cetirizine in children and adolescents.

【 授权许可】

Unknown