期刊论文详细信息
Beilstein Journal of Organic Chemistry | |
Synthesis of functionalized spiro[indoline-3,4’-pyridines] and spiro[indoline-3,4’-pyridinones] via one-pot four-component reactions | |
Li-Juan Zhang1  Chao-Guo Yan1  Jing Sun1  Qun Wu1  | |
[1] College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China; | |
关键词: 1,4-dihydropyridine; electron-deficient alkyne; four-component reaction; isatin; one-pot reaction; spiro compound; | |
DOI : 10.3762/bjoc.9.97 | |
来源: DOAJ |
【 摘 要 】
In the presence of triethylamine as catalyst, the one-pot four-component reactions of arylamines, methyl propiolate, isatin and malononitrile afforded the functionalized spiro[indoline-3,4’-pyridine] derivatives in good yields. Similar reactions with ethyl cyanoacetate successfully afforded the functionalized spiro[indoline-3,4’-pyridines] and spiro[indoline-3,4’-pyridinones] as the main products according to the structures of the arylamines and other primary amines.
【 授权许可】
Unknown