期刊论文详细信息
Journal of Chemical Sciences | |
Efficient, green and solvent-free synthesis of tetrasubstituted imidazoles using SbCl3/SiO2 as heterogeneous catalyst | |
Javad Safari11  Simin Naseh1  Soheila Gandomi-Ravandi1  | |
[1] Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317 51167, Kashan, Iran$$ | |
关键词: Imidazole; solvent-free conditions; four-component reaction; heterogeneous catalyst; Lewis acid.; | |
DOI : | |
来源: Indian Academy of Sciences | |
【 摘 要 】
Antimony trichloride absorbed on silica gel (SbCl3/SiO2) efficiently catalyses the four-component cyclocondensation of 1,2-diketone, aldehyde, ammonium acetate, and primary amine under solvent-free conditions to afford the corresponding tetrasubstituted imidazoles in high yields. The main merit of this study is introducing a novel catalyst to successful synthesis of a wide range of 1,2,4,5-tetrasubstituted imidazoles for the first time. The proposed method involves features such as simplicity, generality, fairly good efficiency, and reusability of the catalyst.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912040508571ZK.pdf | 213KB | download |