Glutamine Synthetase in Legumes: Recent Advances in Enzyme Structure and Functional Genomics

International Journal of Molecular Sciences

关键词: glutamine synthetase;    <;    em>;    Lotus japonicus<;    /em>;    functional genomics;    nitrogen metabolism;   

DOI  :  10.3390/ijms13077994

来源: DOAJ

【 摘 要 】

Glutamine synthetase (GS) is the key enzyme involved in the assimilation of ammonia derived either from nitrate reduction, N₂ fixation, photorespiration or asparagine breakdown. A small gene family is encoding for different cytosolic (GS1) or plastidic (GS2) isoforms in legumes. We summarize here the recent advances carried out concerning the quaternary structure of GS, as well as the functional relationship existing between GS2 and processes such as nodulation, photorespiration and water stress, in this latter case by means of proline production. Functional genomic analysis using GS2-minus mutant reveals the key role of GS2 in the metabolic control of the plants and, more particularly, in carbon metabolism.

【 授权许可】

Unknown