Potential anti-diabetic activity of Bombax ceiba

Bangladesh Journal of Pharmacology

Gokul S. Talele¹  Chetan Bhavsar² 

[1] NGSPM?s College of Pharmacy, Brahma Valley Educational campus, Trimbak road, Anjaneri, Nashik;R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dhule;

关键词: Kantesavar;    Toranmal;    Hypoglycemic;    Hypolipidemic;    Streptozotocin;   

DOI  :  10.3329/bjp.v8i2.13701

来源: DOAJ

【 摘 要 】

Bombax ceiba bark extract was evaluated for its hypoglycemic and hypolipide-mic potential through normal and streptozotocin-induced diabetic rats administered with graded oral doses (200, 400, 600 mg/kg/day) for 21 days. The results showed that a dose of 600 mg/kg of B. ceiba extract is the most effective to cause significant (p<0.001) hypoglycemic and/or hypolipidemic effects on  streptozotocin-induced diabetic rats. This dose also significantly (p<0.001) lowered the total cholesterol and triglyceride level in severely diabetic rats. Phytochemical and GC-MS studies confirmed the presence of the triterpenoid compounds in the extract, which may account for its significant hypoglycemic activity. The present study thus provides a scientific rationale for the traditional use of this plant in the management diabetes.

【 授权许可】

Unknown