Evaluation of polymethylmethacrylate as ocular implant in rabbits subjected to evisceration

Revista Ceres

Deusdete Conceição Gomes Junior¹  Adriana Torrecilhas Jorge Brunelli²  Evandro de Toledo Piza²  Ana Letícia Groszewicz de Souza²  José Luiz Laus³  Arianne Pontes Oriá⁴  Celina Tie Nishimori⁵  Luís Alberto dos Santos⁶  Francisco de Assis Dórea Neto⁷ 

[1] ;IPEV;Universidade Estadual Paulista;Universidade Federal da Bahia;Universidade Federal de Goiás;Universidade Federal do Rio Grande do Sul;União Metropolitana de Educação e Cultura;

关键词: prótese intraocular;    enucleação;    evisceração;   

DOI  :  10.1590/S0034-737X2012000400004

来源: DOAJ

【 摘 要 】

Spheres of different types of material are used for the replacement of lost volume after removal of the eye bulb or its content to prevent contraction of the orbital cavity. The aim of this study was to evaluate the scope of polymethylmethacrylate (PMMA) used as intraocular implant in eviscerated rabbit eye. Twelve New Zealand rabbits underwent unilateral evisceration of the left eye, with subsequent implantation of PMMA sphere 12 mm in diameter. Clinical evaluation was performed daily during the first 15 days after surgery and every 15 days until the end of the study period (180 days). For the histopathological analysis, three animals per trial underwent enucleation at 15, 45, 90 and 180 days after evisceration. There was no wound dehiscence, signs of infection or implant extrusion in any animal throughout the study period. Histological examination revealed the formation of fibrovascular tissue around the implants. The PMMA behaved as inert and non-integrable.

【 授权许可】

Unknown