Evaluation of polymethylmethacrylate as ocular implant in rabbits subjected to evisceration

Revista Ceres

Arianne Pontes Oriá²  Francisco De Assis Dórea Neto¹  Luís Alberto Dos Santos¹  Evandro De Toledo Piza¹  Adriana Torrecilhas Jorge Brunelli¹  Celina Tie Nishimori¹  Ana Letícia Groszewicz De Souza¹  Deusdete Conceição Gomes Junior¹  José Luiz Laus¹ 

[1] ,Universidade Federal da Bahia Departamento de Patologia e Clínicas Salvador Bahia ,Brazil

关键词: intraocular prosthesis;    enucleation;    evisceration;    prótese intraocular;    enucleação;    evisceração;   

DOI  :  10.1590/S0034-737X2012000400004

来源: SciELO

【 摘 要 】

Spheres of different types of material are used for the replacement of lost volume after removal of the eye bulb or its content to prevent contraction of the orbital cavity. The aim of this study was to evaluate the scope of polymethylmethacrylate (PMMA) used as intraocular implant in eviscerated rabbit eye. Twelve New Zealand rabbits underwent unilateral evisceration of the left eye, with subsequent implantation of PMMA sphere 12 mm in diameter. Clinical evaluation was performed daily during the first 15 days after surgery and every 15 days until the end of the study period (180 days). For the histopathological analysis, three animals per trial underwent enucleation at 15, 45, 90 and 180 days after evisceration. There was no wound dehiscence, signs of infection or implant extrusion in any animal throughout the study period. Histological examination revealed the formation of fibrovascular tissue around the implants. The PMMA behaved as inert and non-integrable.

【 授权许可】

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