Modern Wound Dressings: Hydrogel Dressings

Biomedicines

Tatiana Malivanova¹  Valentin Brumberg¹  Tatiana Astrelina¹  Alexander Samoilov¹ 

[1] Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency, 123098 Moscow, Russia;

关键词: acute wounds;    chronic wounds;    semipermeable film dressings;    semipermeable foam dressings;    hydrocolloids;    hydrogels;   

DOI  :  10.3390/biomedicines9091235

来源: DOAJ

【 摘 要 】

Chronic wounds do not progress through the wound healing process in a timely manner and are considered a burden for healthcare system; they are also the most common reason for decrease in patient quality of life. Traditional wound dressings e.g., bandages and gauzes, although highly absorbent and effective for dry to mild, exudating wounds, require regular application, which therefore can cause pain upon dressing change. In addition, they have poor adhesional properties and cannot provide enough drainage for the wound. In this regard, the normalization of the healing process in chronic wounds is an extremely urgent task of public health and requires the creation and implementation of affordable dressings for patients with chronic wounds. Modern wound dressings (WDs) are aimed to solve these issues. At the same time, hydrogels, unlike other types of modern WDs (foam, films, hydrocolloids), have positive degradation properties that makes them the perfect choice in applications where a targeted delivery of bioactive substances to the wound is required. This mini review is focused on different types of traditional and modern WDs with an emphasis on hydrogels. Advantages and disadvantages of traditional and modern WDs as well as their applicability to different chronic wounds are elucidated. Furthermore, an effectiveness comparison between hydrogel WDs and the some of the frequently used biotechnologies in the field of regenerative medicine (adipose-derived mesenchymal stem cells (ADMSCs), mesenchymal stem cells, conditioned media, platelet-rich plasma (PRP)) is provided.

【 授权许可】

Unknown