Insights into the Implications of Coexisting Type 2 Inflammatory Diseases

Journal of Inflammation Research

关键词: type 2 inflammation;    th2 inflammation;    asthma;    atopic dermatitis;    eosinophilic esophagitis;    chronic rhinosinusitis;   

DOI  :  

来源: DOAJ

【 摘 要 】

Justin P McCormick, Jivianne T Lee Department of Head and Neck Surgery, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USACorrespondence: Jivianne T LeeDepartment of Head and Neck Surgery, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USAEmail [e-mail]: The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associated with comorbid conditions in patients. The purpose of this article is to review the evidence behind concurrent Th2-mediated diseases and explore how the presence of these comorbid conditions affect patient and disease outcomes.Keywords: type 2 inflammation, Th2 inflammation, asthma, atopic dermatitis, eosinophilic esophagitis, chronic rhinosinusitis

【 授权许可】

Unknown