A Mutation Network Method for Transmission Analysis of Human Influenza H3N2

Viruses

Xiangjun Du¹  Feng Tang¹  Zicheng Cao¹  Shiwen Liang¹  Yinghan Wang¹  Bing Zhang¹  Wei Shen¹  Haoyu Long¹  Yuelong Shu¹  Jinfeng Zeng¹  Caijun Sun¹  Cai Chen¹  Junbo Bai¹  Chi Zhang¹ 

[1] School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou 510006, China;

关键词: influenza virus;    mutation network;    transmission;    phylogenetic analysis;   

DOI  :  10.3390/v12101125

来源: DOAJ

【 摘 要 】

Characterizing the spatial transmission pattern is critical for better surveillance and control of human influenza. Here, we propose a mutation network framework that utilizes network theory to study the transmission of human influenza H3N2. On the basis of the mutation network, the transmission analysis captured the circulation pattern from a global simulation of human influenza H3N2. Furthermore, this method was applied to explore, in detail, the transmission patterns within Europe, the United States, and China, revealing the regional spread of human influenza H3N2. The mutation network framework proposed here could facilitate the understanding, surveillance, and control of other infectious diseases.

【 授权许可】

Unknown