Recent Technological Developments in the Diagnosis and Treatment of Cerebral Edema

Advanced NanoBiomed Research

Karthikeya P. Deshmukh¹  Ali K. Yetisen¹  Savas Tasoglu²  Sajjad Rahmani Dabbagh²  Nan Jiang³ 

[1] Department of Chemical Engineering Imperial College London Imperial College Road, Kensington London SW7 2AZ UK;Department of Mechanical Engineering Koc University Rumelifeneri Yolu, Sariyer Istanbul 34450 Turkey;West China School of Basic Medical Sciences & Forensic Medicine Sichuan University Chengdu 610041 China;

关键词: acquired brain injuries;    biomarkers;    cerebrospinal fluid;    neuromonitoring;    neurocritical;   

DOI  :  10.1002/anbr.202100001

来源: DOAJ

【 摘 要 】

Latest technological advancements in neurocritical care have translated to improved clinical outcomes and have paved the way for the effective diagnosis and treatment of cerebral edema. Effective management of cerebral edema has the potential to provide a personalized treatment by obtaining the complete pathophysiological information of the patient. The aims of this review are to inform the reader about the research and development in this field in the past decade as well as the materialization of scientific literature through patents. There is a growing interest in multimodal monitoring of the diseased brain as it provides a necessary means to implement effective intervention strategies. Although there is a gradual shift toward the adoption of noninvasive devices for research purposes, their clinical applications are hindered by their inaccuracies. However, the inherent risk of complication and high costs of implementation challenge the status quo. The role of neuroprotectants is explored and the combination of neurodiagnostic and neuroprotective approaches is proposed. Finally, the impacts of the current state of global affairs are discussed and it is predicted that the rising number of traumatic brain injury patents will inevitably translate to improvements in technologies to effectively address cerebral edema.

【 授权许可】

Unknown